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Tetsunori Saikawa Selected Research

geranylgeranylacetone (teprenone)

9/2007Mitochondria are targets for geranylgeranylacetone-induced cardioprotection against ischemia-reperfusion in the rat heart.
7/2005Effects of insulin resistance on geranylgeranylacetone-induced expression of heat shock protein 72 and cardioprotection in high-fat diet rats.
6/2005Oral administration of geranylgeranylacetone blunts the endothelial dysfunction induced by ischemia and reperfusion in the rat heart.
7/2003Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart.

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Tetsunori Saikawa Research Topics

Disease

26Insulin Resistance
08/2012 - 09/2003
14Type 2 Diabetes Mellitus (MODY)
08/2012 - 10/2004
13Atrial Fibrillation
10/2020 - 09/2003
13Reperfusion Injury
01/2016 - 10/2002
10Ischemia
03/2011 - 10/2002
7Fibrosis (Cirrhosis)
01/2016 - 11/2007
7Hyperthermia
01/2012 - 08/2006
5Inflammation (Inflammations)
01/2016 - 01/2008
5Heart Diseases (Heart Disease)
01/2012 - 09/2004
5Ventricular Tachycardia
01/2011 - 11/2003
5Cerebral Infarction
10/2008 - 09/2003
4Hypertension (High Blood Pressure)
04/2011 - 10/2006
4Chronic Kidney Failure (Chronic Renal Failure)
10/2008 - 05/2006
4Atherosclerosis
01/2008 - 09/2007
4Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
02/2007 - 09/2003
3Hemorrhage
08/2015 - 09/2003
3Diabetes Mellitus
10/2014 - 05/2012
3Infarction (Infarctions)
07/2012 - 05/2009
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2011 - 03/2004
3Heart Failure
01/2011 - 09/2003
3Myocardial Infarction
01/2011 - 02/2009
3Essential Hypertension
08/2008 - 07/2005
2Cardiovascular Diseases (Cardiovascular Disease)
11/2020 - 09/2008
2Thromboembolism
06/2016 - 08/2015
2Cognitive Dysfunction
07/2011 - 04/2011
2Stroke (Strokes)
01/2011 - 07/2010
2Cardiac Arrhythmias (Arrythmia)
01/2011 - 05/2005
2Glucose Intolerance
08/2008 - 06/2008
2Hypoxia (Hypoxemia)
07/2007 - 05/2006
2Hyperhomocysteinemia
01/2007 - 05/2006
1Diabetes Complications
01/2016
1Starvation
01/2016
1Atrial Remodeling
01/2016
1Thrombosis (Thrombus)
01/2013
1Sarcoidosis (Schaumann Disease)
04/2012

Drug/Important Bio-Agent (IBA)

22Insulin (Novolin)FDA Link
01/2016 - 10/2002
9HSP72 Heat-Shock ProteinsIBA
12/2011 - 07/2003
8Glucose (Dextrose)FDA LinkGeneric
01/2016 - 07/2005
7Angiotensin IIIBA
04/2013 - 06/2004
6C-Reactive ProteinIBA
10/2011 - 04/2005
4Streptozocin (Streptozotocin)FDA Link
01/2016 - 10/2002
4Pioglitazone (Actos)FDA Link
01/2012 - 08/2006
4candesartanIBA
12/2011 - 06/2004
4Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2011 - 02/2009
4geranylgeranylacetone (teprenone)IBA
09/2007 - 07/2003
3LipidsIBA
11/2020 - 12/2004
3Warfarin (Coumadin)FDA LinkGeneric
06/2016 - 01/2013
3AnticoagulantsIBA
08/2015 - 10/2010
3Reactive Oxygen Species (Oxygen Radicals)IBA
10/2014 - 07/2010
3AntioxidantsIBA
12/2012 - 03/2011
3AdiponectinIBA
08/2012 - 07/2007
3Pravastatin (Pravachol)FDA LinkGeneric
01/2012 - 06/2010
3Phosphatidylinositols (Phosphatidylinositol)IBA
12/2011 - 08/2006
3Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
12/2011 - 08/2006
3HomocysteineIBA
07/2011 - 10/2007
3Angiotensin Receptor AntagonistsIBA
04/2011 - 06/2004
3CalciumIBA
01/2011 - 03/2004
3Creatine Kinase (Creatine Phosphokinase)IBA
05/2009 - 11/2003
3HDL CholesterolIBA
06/2008 - 02/2007
3AlbuminsIBA
09/2007 - 10/2004
2Ezetimibe (Zetia)FDA Link
11/2020 - 01/2012
2Protein Kinase CIBA
10/2020 - 11/2003
2LDL CholesterolIBA
01/2012 - 06/2008
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2012 - 02/2011
2Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2012 - 07/2005
2Amlodipine (Norvasc)FDA LinkGeneric
04/2011 - 10/2006
2Pharmaceutical PreparationsIBA
03/2011 - 09/2007
2Anti-Arrhythmia AgentsIBA
01/2011 - 10/2006
2Valsartan (Vals)FDA Link
09/2010 - 07/2005
2mitochondrial K(ATP) channelIBA
05/2009 - 09/2007
2AdrenomedullinIBA
03/2009 - 06/2005
2Atorvastatin (Lipitor)FDA Link
02/2009 - 06/2008
2Angiotensin II Type 1 Receptor BlockersIBA
10/2006 - 09/2004
2Glyburide (Glibenclamide)FDA LinkGeneric
08/2006 - 11/2003
1Phosphotransferases (Kinase)IBA
10/2020
1GlycogenIBA
10/2020
1Interleukin-10 (Interleukin 10)IBA
01/2016
1salicylhydroxamic acid (SHAM)IBA
01/2016
1MicroRNAs (MicroRNA)IBA
01/2016
1Factor Xa InhibitorsIBA
08/2015
1CollagenIBA
10/2014
1Collagen Type I (Type I Collagen)IBA
10/2014
1LeptinIBA
04/2013
1SmokeIBA
01/2013
1NADPH Oxidases (NAD(P)H oxidase)IBA
12/2012
1AdipokinesIBA
08/2012
1ResveratrolIBA
07/2012
1Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA
05/2012
1Adrenal Cortex Hormones (Corticosteroids)IBA
04/2012
1NADP (NADPH)IBA
01/2012
1CholesterolIBA
01/2012
1Iodine-123IBA
01/2012

Therapy/Procedure

8Therapeutics
06/2016 - 09/2003
4Renal Dialysis (Hemodialysis)
10/2008 - 05/2006
2Catheter Ablation
01/2013 - 02/2009
2Intravenous Administration
01/2007 - 09/2003
2Induced Hyperthermia (Thermotherapy)
05/2006 - 11/2004
2Oral Administration
06/2005 - 07/2003
1Splenectomy
01/2016
1Electric Countershock (Cardioversion)
01/2013